A concise route to the highly-functionalized azetidine precursor: the enantioselective synthesis of penaresidin B
| Autor: | Xue-Wei Liu, Feiqing Ding, Si Min Kock, Min Li Leow, Ronny William |
|---|---|
| Přispěvatelé: | School of Physical and Mathematical Sciences |
| Rok vydání: | 2015 |
| Předmět: |
Glycosylation
glycosylation Glycal Stereochemistry Azetidine Molecular Conformation Aldehyde Catalysis chemistry.chemical_compound Materials Chemistry chemistry.chemical_classification Aldehydes Metals and Alloys Enantioselective synthesis Stereoisomerism General Chemistry Surfaces Coatings and Films Electronic Optical and Magnetic Materials Penaresidin B chemistry Ceramics and Composites Azetidines Stereoselectivity Hydroamination azetidine Fatty Alcohols |
| Zdroj: | Chemical communications (Cambridge, England). 51(22) |
| ISSN: | 1364-548X |
| Popis: | An efficient and high-yielding synthesis of penaresidin B is disclosed herein. The concise 8-step synthesis of azetidine aldehyde was devised by incorporating our novel strategy for ready access to 3-amino-2,3-dideoxysugars via regio- and stereoselective tandem hydroamination/glycosylation of glycal as the key step. MOE (Min. of Education, S’pore) Published version |
| Databáze: | OpenAIRE |
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