Modulation of spinal shape with growth following implantation of a novel surgical implant

Autor: Enzo Vettorato, Gudrun Schöffmann, J. N. Alastair Gibson, John G. Burke, R Eddie Clutton, Tim Drew
Rok vydání: 2014
Předmět:
Zdroj: European Spine Journal. 24:1522-1532
ISSN: 1432-0932
0940-6719
DOI: 10.1007/s00586-014-3610-6
Popis: First, to determine whether scoliosis development could be limited or reversed by growth when a novel modular hinged implant was fixed to the convexity of a scoliosis created by contralateral rib and laminar tethering and unilateral rib resection in a sheep model. Second, to assess the effect and performance of the implant in normal non-tethered sheep. At 5 weeks, 20 Scottish Blackface lambs underwent surgery to create a right sided scoliosis by (i) tethering the left lamina of T5–L1 and the left lower six ribs and (ii) resecting a segment of their right lower six ribs [1, 2]. Twelve weeks later, through an antero-lateral thoracotomy, a mobile bi-planar hinged implant was inserted onto the right side of the spine of eight animals (group 1). For comparison, 12 sheep were tethered only but had no implant insertion (group 2). In addition, seven had no tethering but were implanted (group 3) and normal growth patterns were observed in five that had no surgery (group 4). Curve progression was assessed by plain radiography and CT over a 1-year period. Before implant insertion the trial animals had a scoliosis of 35o ± 16o and a lordosis of 44o ± 20o (n = 8, mean ± SD). Surgery immediately reduced these values to 25o ± 14o, p
Databáze: OpenAIRE
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