Usefulness and feasibility of repeated tail artery cannulations in the rat

Autor: Kosuke Kumagai, Arata Tomiyama, Terushige Toyooka, Yohei Otsuka, Koichi Kurihara, Kojiro Wada, Kentaro Yamada, Masahiro Horikawa, Satoru Takeuchi
Rok vydání: 2021
Předmět:
Zdroj: Blood Pressure Monitoring. 26:230-233
ISSN: 1359-5237
DOI: 10.1097/mbp.0000000000000522
Popis: Rat ventral caudal artery (VCA, tail artery) cannulation for blood pressure monitoring and blood sampling is essential for maintaining consistent procedures in rat models. Double or triple insults are sometimes necessary, but repeated VCA cannulations have not been compared with repeated femoral artery cannulations. In addition, the collateral system for resistance to ischemia in the rat tail is unclear. Our present study revealed that repeated VCA cannulations on different days was a better technique than repeated femoral artery cannulations in terms of surgical time, postsurgical weight loss and ischemic complications. Furthermore, the lateral caudal arteries and the segmental anastomosing vessels were important for resistance to ischemic complications after VCA occlusion.
Databáze: OpenAIRE