Increasing the noninvasive management of rhesus isoimmunization
| Autor: | Nikolaos Papantoniou, Aris Antsaklis, George Daskalakis, S. Mesogitis, E. Anastasakis, Spyros Marinopoulos |
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| Rok vydání: | 2008 |
| Předmět: |
Middle Cerebral Artery
medicine.medical_specialty Anemia Gestational Age Hematocrit Rh Isoimmunization Ultrasonography Prenatal Hemoglobins Pregnancy medicine.artery Humans Medicine Ultrasonography Doppler Color Greece medicine.diagnostic_test business.industry Obstetrics Rhesus Isoimmunization Pregnancy Complications Hematologic Pregnancy Outcome Obstetrics and Gynecology Gestational age General Medicine Fetal Blood medicine.disease Confidence interval Fetal Diseases Middle cerebral artery Gestation Female Cordocentesis business Blood Flow Velocity circulatory and respiratory physiology |
| Zdroj: | International Journal of Gynecology & Obstetrics. 101:281-284 |
| ISSN: | 0020-7292 |
| Popis: | Objective To determine the clinical outcome of isoimmunized pregnancies managed by middle cerebral artery peak systolic velocity (MCA-PSV) in an intention-to-treat study. Method Rhesus isoimmunized pregnancies were managed with serial ultrasound and Doppler studies at 7-day intervals up to 34 weeks of gestation, between 2001 and 2005. Invasive diagnostic and therapeutic procedures were carried out when MCA-PSV was indicative of moderate or severe anemia. Results The overall sensitivity in detecting moderate to severe fetal anemia at less than 34 weeks was 100% (95% confidence interval, 54.1–100.0 L). Twenty-two cases were managed with MCA-PSV. Twelve cases needed fetal blood sampling and 6 cases needed intrauterine transfusion. Cordocentesis revealed a hematocrit of more than 26% in 6 fetuses. Conclusion Management by MCA-PSV Doppler at weekly intervals is a highly sensitive method for detecting fetal anemia. It reduces the number of fetal blood samples needed and significantly lowers interventional procedures. |
| Databáze: | OpenAIRE |
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