The role of a chest computed tomography severity score in coronavirus disease 2019 pneumonia

Autor: Andrea Agostini, Marika Tardella, Marco Di Carlo, Andrea Giovagnoni, Alessandra Borgheresi, Fausto Salaffi, Piercarlo Sarzi-Puttini, Minorati D, Marina Carotti, Daniela Marotto, Massimo Galli
Rok vydání: 2020
Předmět:
Adult
Male
medicine.medical_specialty
Coronavirus disease 2019 (COVID-19)
Pneumonia
Viral
Air bronchogram
Observational Study
Computed tomography
macromolecular substances
outcomes
acute respiratory disease
03 medical and health sciences
Betacoronavirus
coronavirus disease 2019
0302 clinical medicine
Respiratory Rate
medicine
Humans
pneumonia
risk factors
030212 general & internal medicine
Lung
Pandemics
Aged
medicine.diagnostic_test
Receiver operating characteristic
business.industry
SARS-CoV-2
Curve analysis
COVID-19
chest computed tomography
General Medicine
predictive score
Middle Aged
Prognosis
Oxygen
medicine.anatomical_structure
ROC Curve
030220 oncology & carcinogenesis
Female
Tomography
Radiology
business
Coronavirus Infections
Tomography
X-Ray Computed
Grading scale
Research Article
Zdroj: Medicine
ISSN: 1536-5964
Popis: The chest computed tomography (CT) characteristics of coronavirus disease 2019 (COVID-19) are important for diagnostic and prognostic purposes. The aim of this study was to investigate chest CT findings in COVID-19 patients in order to determine the optimal cut-off value of a CT severity score that can be considered a potential prognostic indicator of a severe/critical outcome. The CT findings were evaluated by means of a severity score that included the extent (0–4 grading scale) and nature (0–4 grading scale) of CT abnormalities. The images were evaluated at 3 levels bilaterally. A receiver operating characteristics (ROC) curve was used to identify the optimal score (Youden's index) predicting severe/critical COVID-19. The study involved 165 COVID-19 patients (131 men [79.4%] and 34 women [20.6%] with a mean age of 61.5 ± 12.5 years), of whom 30 (18.2%) had severe/critical disease and 135 (81.8%) mild/typical disease. The most frequent CT finding was bilateral predominantly subpleural and basilar airspace changes, with more extensive ground-glass opacities than consolidation. CT findings of consolidation, a crazy-paving pattern, linear opacities, air bronchogram, and extrapulmonary lesions correlated with severe/critical COVID-19. The mean CT severity score was 63.95 in the severe/critical group, and 35.62 in the mild/typical group (P
Databáze: OpenAIRE
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