Age of exposure to infections and risk of childhood leukaemia
| Autor: | D Kassimos, Stavros Haidas, V. Flytzani, Helen Kosmidis, Eleni Petridou, Donald Tong, Dimitrios Trichopoulos, Maria Kalmanti |
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| Předmět: |
education.field_of_study
Pediatrics medicine.medical_specialty Childhood leukemia business.industry Population General Engineering Case-control study Attendance General Medicine Environmental exposure Day care medicine.disease Birth order Relative risk medicine General Earth and Planetary Sciences education business General Environmental Science |
| Zdroj: | Scopus-Elsevier |
| Popis: | Between January and August 1992 in Greece researchers conducted telephone interviews with parents of children with leukemia (136 cases most in Attica [Athens and its environs] and the others on the island of Crete) and with parents of children not afflicted with leukemia (187 controls) to determine whether childhood leukemia may be a result of a subclinical infection at an earlier age. They controlled for place of residence when they conducted the multiple logistic regression analyses. They used attendance at a day care facility as a proxy for earlier infection because children come in close contact with each other at day cares thereby exposing them to many infectious agents. Children who attended a day care had a lower relative risk of developing leukemia than those who did not attend day care (.67) but attendance did not have a significant protective effect. It did appear to have a significant protective effect for children who attended day care during infancy (for at least 3 months during the first 2 years of life) however (relative risk = .28; p = .03). Significance remained even when the researchers considered different operational definitions of early attendance. Exposure to magnetic fields appeared to have a protective effect also against the development of childhood leukemia but this effect did not reach significance (p = .07). The relative risk for |
| Databáze: | OpenAIRE |
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