Deficiency of Growth Hormone in an Adult Man Case of Idiopathic Adrenocorticotropin Deficiency
| Autor: | Ken Tomotsune, Toshihiro Suda, Kazunori Kageyama, Yuko Tsushima, Satoru Sakihara, Miyuki Yanagimachi |
|---|---|
| Rok vydání: | 2009 |
| Předmět: |
Male
endocrine system medicine.medical_specialty Hydrocortisone Hypopituitarism Growth hormone Adrenocorticotropic Hormone Internal medicine Internal Medicine medicine Humans Glucocorticoids business.industry Insulin tolerance test Adrenocorticotropin deficiency General Medicine Middle Aged medicine.disease Growth hormone secretion Treatment Outcome Endocrinology Hypothalamus Growth Hormone business hormones hormone substitutes and hormone antagonists Glucocorticoid medicine.drug |
| Zdroj: | Internal Medicine. 48:607-610 |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.48.1897 |
| Popis: | Growth hormone (GH) deficiency is transient in most cases of adrenocorticotropin (ACTH) deficiency, while deficiency of both selective ACTH and GH in adults, as in the present case, is rare among hypopituitarism cases. In this patient, one year after hydrocortisone replacement for ACTH deficiency, data on GH secretion by insulin tolerance test and GH-releasing peptide-2 injection showed a partial improvement, but still there was lack of an adequate response. We consider that the patient had the deficiency of both selective GH and ACTH. Therefore, careful monitoring of GH function after the glucocorticoid replacement is required in cases of ACTH deficiency. |
| Databáze: | OpenAIRE |
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