Infection control response to an outbreak of OXA-23 carbapenemase-producing carbapenem-resistant Acinetobacter baumannii in a skilled nursing facility in Utah
| Autor: | Anna L Sangster, Maureen Vowles, Jennifer Wagner, James Stewart, Roberta Horth, Hailey Schuckel, Kelly F. Oakeson, Erin L Young, Randon Gruninger, Allyn Nakashima, Alessandro Rossi, Linda Rider, Lori Smith, Amanda R. Smith |
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| Rok vydání: | 2021 |
| Předmět: |
Acinetobacter baumannii
medicine.medical_specialty Epidemiology Microbial Sensitivity Tests beta-Lactamases Article Disease Outbreaks 03 medical and health sciences 0302 clinical medicine Bacterial Proteins Utah Humans Medicine Infection control Colonization 030212 general & internal medicine Skilled Nursing Facilities Cross Infection Infection Control 0303 health sciences biology 030306 microbiology business.industry Transmission (medicine) Health Policy Public health Public Health Environmental and Occupational Health Outbreak Carbapenemase producing biology.organism_classification Anti-Bacterial Agents Infectious Diseases Carbapenems Emergency medicine Skilled Nursing Facility business Acinetobacter Infections |
| Zdroj: | Am J Infect Control |
| ISSN: | 0196-6553 |
| Popis: | Background Antibiotic-resistant Acinetobacter species are a growing public health threat, yet are not nationally notifiable, and most states do not mandate reporting. Additionally, there are no standardized methods to detect Acinetobacter species colonization. Methods An outbreak of carbapenem-resistant Acinetobacter baumannii (CRAB) was identified at a Utah ventilator unit in a skilled nursing facility. An investigation was conducted to identify transmission modes in order to control spread of CRAB. Culture-based methods were used to identify patient colonization and environmental contamination in the facility. Results Of the 47 patients screened, OXA-23-producing CRAB were detected in 10 patients (21%), with 7 patients (15%) having been transferred from out-of-state facilities. Of patients who screened positive, 60% did not exhibit any signs or symptoms of active infection by chart review. A total of 38 environmental samples were collected and CRAB was recovered from 37% of those samples. Whole genome sequencing analyses of patient and environmental isolates suggested repeated CRAB introduction into the facility and highlighted the role of shared equipment in transmission. Conclusions The investigation demonstrated this ventilated skilled nursing facility was an important reservoir for CRAB in the community and highlights the need for improved surveillance, strengthened infection control and inter-facility communication within and across states. |
| Databáze: | OpenAIRE |
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