Bimodal immunoglobulin A gammopathy in a cat with feline myeloma-related disorders
| Autor: | Yumiko Shimoyama, Kenji Baba, Yumi Hirata, Satoshi Kambayashi, Takuya Mizuno, Masaya Igase, Miki Iwata, Takako Shimokawa Miyama, Masaru Okuda, Hiroko Hiraoka |
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| Rok vydání: | 2016 |
| Předmět: |
Immunoglobulin A
Immunofixation Pathology medicine.medical_specialty 040301 veterinary sciences Paraproteinemias Spleen Immunoelectrophoresis Cat Diseases 0403 veterinary science Gammopathy Internal Medicine medicine Animals feline Multiple myeloma General Veterinary biology medicine.diagnostic_test business.industry immunofixation 0402 animal and dairy science 04 agricultural and veterinary sciences Note medicine.disease 040201 dairy & animal science medicine.anatomical_structure oncology Immunology Cats biology.protein plasma cell disorder Neoplastic cell hyperproteinemia Female Antibody Multiple Myeloma business |
| Zdroj: | The Journal of Veterinary Medical Science |
| ISSN: | 1347-7439 0916-7250 |
| Popis: | A 10-year-old female spayed mixed breed cat with a subcutaneous mass on the right hind limb was revealed with bimodal monoclonal gammopathy composed of IgA by immunoelectrophoresis and immunofixation. Approximately 1 month after referral, the cat died due to renal failure. Postmortem immunohistopathologic evaluation of the subcutaneous mass revealed neoplastic cell proliferation of plasma cells and giant myeloma cells. Neoplastic cells were also present in the liver and spleen. These results led to the diagnosis of a rare case of feline myeloma-related disorders with extramedullary plasmacytoma infiltrating in multiple locations. This report emphasizes the necessity to accumulate cases with similar clinicopathologic findings in the future. |
| Databáze: | OpenAIRE |
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