Variegated expression of the Sgs-4 locus in Drosophila melanogaster
| Autor: | Kornher Js, Kauffman Sa |
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| Rok vydání: | 1986 |
| Předmět: |
Male
Transcription Genetic Locus (genetics) Biology Salivary Glands Translocation Genetic stomatognathic system Genetics medicine RNA Messenger Salivary Proteins and Peptides Gene Genetics (clinical) Salivary gland Glue Proteins Drosophila DNA biology.organism_classification Drosophila melanogaster Phenotype medicine.anatomical_structure Position effect Gene Expression Regulation Larva Instar Female Developmental biology |
| Zdroj: | Chromosoma. 94:205-216 |
| ISSN: | 1432-0886 0009-5915 |
| DOI: | 10.1007/bf00288495 |
| Popis: | Experiments on T(1;4)wm258-21 larvae of Drosophila melanogaster are described which establish the existence of a salivary gland specific marker for position-effect variegation. The marker is a glue protein gene called Sgs-4 which is expressed during the third larval instar. Using temperature as a variegation modifier, we showed that cytological compaction for the Sgs-4 chromosomal locus is enhanced at 17 degrees C and reduced at 29 degrees C. We also found that the Sgs-4 protein and transcript from salivary glands at 17 degrees C accumulate to roughly half the levels found in salivary glands at 29 degrees C. Southern analysis suggested that the Sgs-4 locus at 17 degrees C is polytenized to roughly one-third the level at 29 degrees C. The results are discussed with respect to alternative models of variegation. |
| Databáze: | OpenAIRE |
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