Relationship Between Smoking, Thyroid Volume and Thyrotropin Level in Women and Men in Novosibirsk
| Autor: | S K Malutina, A Ryabikiv, Yu Shepina, L Sherbakova, u Nikitin, Svetlana V. Mustafina, S Shachmatov, Oksana D. Rymar, G Simonova |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Gynecology
medicine.medical_specialty Goiter medicine.diagnostic_test Smoking habit Obstetrics business.industry Thyroid Physical examination Context (language use) General Medicine Odds ratio Urine RC648-665 medicine.disease Diseases of the endocrine glands. Clinical endocrinology Spot urine medicine.anatomical_structure medicine business |
| Zdroj: | Клиническая и экспериментальная тиреоидология, Vol 3, Iss 4, Pp 44-48 (2007) |
| ISSN: | 2310-3787 1995-5472 |
| DOI: | 10.14341/ket20073444-48 |
| Popis: | Purpose: to determine association between smoking habits, thyroid volume and serum TSH. METHODS: in context of internationals projects Monika (1995; age group 25—34) and HAPIEE (2005; age group 45—69) were formed representational groups of Novosibirsk. Were examinated 960 randomly selected participants. Ultrasonic scanning, clinical examination of the thyroid, serum TSH, Т4 were performed to every second. Was analyzed iodine concentration in spot urine samples. Smoking habits were investigated with questionnaires and interviews. Persons, smoking no less than one cigarette a day, were reputed as smokers. RESULTS: smokers part in the age of 25—34 was 47.5%: men — 67%, women — 28%, smokers part in the age of 45—69 was 32%: men — 52%, women — 15.5%. Median of iodine concentration in urine was: 47 microg/g in age group of 25—34 (1995 г), 107 microg/g in age group of 45—69 (2005). Thyroid volume at ultrasonic scanning was positively associated with smoking habits (p < 0.01); current smoking was strongly associated with the risk of goiter in women (odds ratio [OR] = 2.7, 95% [CI]: 1.02—7.2). Serum TSH levels to be lower in smokers than non-smokers and this has a significant bias to men than women, p = 0.001 (age group 45—69). No association was found between of solitary or multiple thyroid nodules with smoking habits. |
| Databáze: | OpenAIRE |
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