Toxoplasma gondii, HCV, and HBV seroprevalence and co-infection among HIV-positive and -negative pregnant women in Burkina Faso
| Autor: | Aly Savadogo, Virginio Pietra, Maria Esposito, Salvatore Musumeci, Salvatore Pignatelli, Jacques Simpore, D. Ilboudo, Marie Christelle Nadambega, Justine Yara |
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| Rok vydání: | 2006 |
| Předmět: |
Adult
Adolescent Prevalence Antibodies Protozoan Antibodies Viral medicine.disease_cause Serology Acquired immunodeficiency syndrome (AIDS) Pregnancy Seroepidemiologic Studies Virology Burkina Faso HIV Seropositivity parasitic diseases Humans Medicine Seroprevalence Hepatitis B virus biology business.industry virus diseases Toxoplasma gondii Middle Aged Hepatitis B medicine.disease biology.organism_classification Hepatitis C digestive system diseases Infectious Diseases Female Viral disease business Serostatus Toxoplasmosis |
| Zdroj: | Journal of Medical Virology. 78:730-733 |
| ISSN: | 1096-9071 0146-6615 |
| Popis: | Toxoplasma gondii (T. gondii) infections can cause serious complications in HIV-infected pregnant women, leading to miscarriage, stillbirth, birth defects (e.g., mental retardation, blindness, epilepsy etc.) and could favor or enhance the mother-to-child transmission of HCV, HBV, and HIV vertical transmission. From May 20, 2004 to August 3, 2005, 336 18-45 years aged pregnant women, were enrolled for an investigation of the prevalence of serum antibodies against T. gondii, HCV, HBV, and HIV using ELISA. The prevalence of T. gondii, HCV, and HBV in pregnant women was 25.3%, 5.4%, and 9.8%, respectively and the HIV serostatus (61.6%) seems to be associated with greater prevalence rates of both T. gondii (28.5% vs. 20.2%) and HBV (11.6% vs. 7.0%). Without taking into account HIV, only 65.5% (220 of 336) of the women were not infected with these agents. The co-infection rate between HIV-infected and -negative women was different statistically: T. gondii/HBV 0.048 versus 0.015, T. gondii/HCV 0.014 versus 0.008, and HCV/HBV 0.005 versus 0.008, respectively. The elevated co-infection rate in HIV-positive women demonstrated that they are exposed to T. gondii, HCV, and HBV infections prevalently by sexual contact. |
| Databáze: | OpenAIRE |
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