Activity of nadifloxacin and three other antimicrobial agents against Cutibacterium acnes isolated from patients with acne vulgaris

Autor: C. Neumeister, Claudia Borelli, M.R. Götz, Rolf-Hasso Bödeker, Constanze Krüger, Pietro Nenoff, U. Schwantes, Daniela Koch
Rok vydání: 2021
Předmět:
Zdroj: Journal of the European Academy of Dermatology and Venereology
ISSN: 1468-3083
0926-9959
Popis: Nadifloxacin (OPC-7251) represents an established antimicrobial agent belonging to the quinolone group and was developed exclusively for topical administration. Nadifloxacin is effective in treating a variety of bacterial skin infections and acne. Here, the in vitro activity of nadifloxacin was assessed and compared with those of erythromycin, clindamycin and tetracycline against Cutibacterium (C.) acnes, formerly Propionibacterium acnes, to gain a picture of the resistance situation in Germany. The study was approved by the Ethics Committee of the Bayerische Landesarztekammer (Munich, Germany; EC-No.17088) and registered at Deutsches Register Klinische Studien (ID:DRKS00014231).
Databáze: OpenAIRE