Hypoglycemia in a Patient with Hypercortisolism and Adrenocortical Carcinoma: A Paradoxical Entity
| Autor: | Tejaswini Maganti, Shobha Mandal, Vineela Kasireddy, Subash Ghimire, Sushmita Khadka, Barbara MolsKowalczewski |
|---|---|
| Rok vydání: | 2022 |
| Předmět: |
Poor prognosis
Pediatrics medicine.medical_specialty Hypoglycemia 03 medical and health sciences Cushing syndrome 0302 clinical medicine Adrenocortical Carcinoma Carcinoma medicine Humans Adrenocortical carcinoma 030212 general & internal medicine Young adult Cushing Syndrome business.industry Prognosis medicine.disease Adrenal Cortex Neoplasms Pathophysiology Oncology 030220 oncology & carcinogenesis Pediatrics Perinatology and Child Health business Hormone |
| Zdroj: | Journal of Adolescent and Young Adult Oncology. 11:122-125 |
| ISSN: | 2156-535X 2156-5333 |
| DOI: | 10.1089/jayao.2020.0229 |
| Popis: | Adrenal cortical carcinoma is a rare and aggressive cancer with poor prognosis. Cases usually present with signs and symptoms of excessive hormone production. Hyperglycemia and Cushing syndrome are common, but tumor-associated hypoglycemia due to paraneoplastic secretion of insulin-like growth factor-2 (termed Anderson's syndrome) is uncommon. Given the rarity of adrenal cortical carcinoma, diagnosis and management of associated complications is challenging. In this study, we present a case of metastatic adrenal cortical carcinoma with a myriad of hormonal abnormalities. We will also briefly review literature regarding genetic association, pathophysiology, treatment options, and prognosis. |
| Databáze: | OpenAIRE |
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