Calcific aortic valve disease should not be considered as a degenerative disease anymore
| Autor: | Cheng Lin Hu, Cong Xin Huang, Jun Liu, Qi-Zhu Tang, Yan Bo Li |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Aortic valve disease
medicine.medical_specialty business.industry Heart Valve Diseases Models Cardiovascular Calcinosis Angiotensin-Converting Enzyme Inhibitors General Medicine medicine.disease Surgery Degenerative disease Aortic Valve Internal medicine cardiovascular system Cardiology Humans Medicine Hydroxymethylglutaryl-CoA Reductase Inhibitors business Aged |
| Zdroj: | Medical Hypotheses. 68:1233-1235 |
| ISSN: | 0306-9877 |
| Popis: | Calcific aortic valve disease is common among the elderly. Until recently, the concept that calcific aortic valve disease is a degenerative and unmodifiable process basically induced by long-lasting mechanical stress was generally accepted. However calcific aortic valve disease is not merely related to age-associated "wear and tear". The development and progression of calcific aortic valve disease are based on an active process that shares a number of similarities with atherosclerosis. Statins and angiotensin-converting enzyme inhibitors have been shown to slow calcium accumulation in aortic valves. Thus, calcific aortic valve disease should not be considered as a degenerative disease anymore. |
| Databáze: | OpenAIRE |
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