One-Pot Synthesis of 7,9-Dialkylpurin-8-one Analogues: Broad Substrate Scope

Autor: Yu Huang, Hai-Ming Guo, Ming-Sheng Xie, Wang Haixia, Hong-Ying Niu, Gui-Rong Qu, Bo-Wen Qin, Jian-Ping Li
Rok vydání: 2013
Předmět:
Zdroj: The Journal of Organic Chemistry. 78:12629-12636
ISSN: 1520-6904
0022-3263
Popis: The one-pot and direct synthesis of 7,9-dialkylpurin-8-one analogues with broad substrate scope has been developed. This copper-catalyzed C-H oxidation reaction could avoid multistep synthesis of quaternary ammonium salts and expand the scope of halogenated alkanes. Moreover, benzimidazole derivatives are also applicable in the catalytic system.
Databáze: OpenAIRE