Relationship between serum cholinesterase level and urinary bladder activity in patients with or without overactive bladder and/or neurogenic bladder
| Autor: | Kimio Sugaya, Minoru Miyazato, Yoshihide Ogawa, Tomohiro Onaga, Yoshinori Oshiro, Atsushi Uchida, Saori Nishijima, Sanehiro Hokama |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Male
medicine.medical_specialty Urinary Bladder Serum albumin Urology urologic and male genital diseases General Biochemistry Genetics and Molecular Biology medicine Cholinesterases Humans In patient Urinary Bladder Neurogenic Serum Albumin Total protein Urinary bladder Serum cholinesterase biology Urinary Bladder Overactive business.industry General Medicine medicine.disease Serum cholinesterase level Response to treatment humanities female genital diseases and pregnancy complications medicine.anatomical_structure Overactive bladder biology.protein Female business |
| Zdroj: | Biomedical Research. 28:287-294 |
| ISSN: | 1880-313X 0388-6107 |
| Popis: | We compared the serum cholinesterase (ChE) level and various parameters between patients with or without overactive bladder (OAB) and/or neurogenic bladder (NB). A total of 258 patients who met the following criteria were enrolled: the presence/absence of OAB and/or NB was documented, laboratory data were available, and liver and renal functions were normal. Patients were divided into the 3 groups: 1) a NB+/OAB+ group who had both NB and OAB, 2) a NB-/OAB+ group who had OAB alone, and 3) an OAB- group who did not have OAB. The relationship between the presence of OAB and various biochemical parameters were examined, as well as the therapeutic outcome in relation to the same biochemical parameters. Forty-three patients had both NB and OAB (NB+/OAB+), 66 patients had OAB without NB (NB-/OAB+), and 149 patients had no OAB (OAB-). Serum ChE, total protein, and albumin levels were lower in the NB-/OAB+ group than the NB+/OAB+ group or the OAB- group. In the NB-/OAB+ group, a higher serum albumin or ChE level was associated with a better therapeutic outcome. These results suggest that a decrease of serum ChE level is related to the occurrence of OAB and the poor response to treatment in OAB patients without NB. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|