Cytotoxic Lesions of the Corpus Callosum Caused by Thermogenic Dietary Supplements
| Autor: | V. Higuera-Ortiz, A.J. Vázquez-Mézquita, Javier Andrés Galnares-Olalde, G. Gómez-Garza, D. Reyes-Vázquez, A. Mendez-Dominguez, Marco Antonio Alegría-Loyola |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Adult
Population Physiology Corpus callosum 030218 nuclear medicine & medical imaging Corpus Callosum Lesion 03 medical and health sciences Young Adult 0302 clinical medicine Leukoencephalopathies medicine Effective diffusion coefficient Cytotoxic T cell Humans Radiology Nuclear Medicine and imaging education education.field_of_study business.industry Adult Brain medicine.disease Discontinuation Toxic leukoencephalopathy Diffusion Magnetic Resonance Imaging Dietary Supplements Female Neurology (clinical) medicine.symptom Entire corpus callosum business 030217 neurology & neurosurgery |
| Zdroj: | AJNR Am J Neuroradiol |
| ISSN: | 1936-959X |
| Popis: | SUMMARY: Consumption of over-the-counter dietary supplements to reduce body weight is common among the population. Thermogenics are herbal combinations that claim to produce a fat-burning process through an increase in the cellular metabolic rate and greater cellular energy consumption, having a high risk for patients developing toxic leukoencephalopathy. We present a series of 6 patients with acute neurologic symptoms and MR imaging showing restricted diffusion and decreased apparent diffusion coefficient values (mean value, 400 mm2/s × 10−6) in the entire corpus callosum compatible with a cytotoxic lesion of the corpus callosum. Although patients responded favorably to the product discontinuation with rapid recovery of neurologic symptoms, there was a more prolonged resolution on imaging alterations. Because of the widespread availability and unregulated nature of thermogenic dietary supplements, physicians must be aware of the clinical and radiologic characteristics of these potential complications of their use. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|