Engineered multicompartment vesicosomes for selective uptake by living cells

Autor: Vasiliy S. Chernyshev, Daniil Nozdriukhin, Roman Chuprov-Netochin, Ekaterina Tsydenzhapova, Marina Novoselova, Dmitry Gorin, Alexey Yashchenok
Rok vydání: 2022
Předmět:
Zdroj: Colloids and surfaces. B, Biointerfaces. 220
ISSN: 1873-4367
Popis: Small extracellular vesicles (sEVs) have attracted tremendous interest in recent years due to their exceptional properties for therapeutic and diagnostic applications. Although much research was focused on the quantity and content of sEVs, less efforts have been put into discovering the interaction between sEVs and cells. Here we engineered multicompartment particles, termed vesicosomes, by deposition of sEVs derived from MCF7, CHO cells and human plasma onto the surface of polyelectrolyte (PE)-coated silica (SiO
Databáze: OpenAIRE