Comparison of Outcomes Between Combined Transepithelial Photorefractive Keratectomy With and Without Accelerated Corneal Collagen Cross-Linking: A 1-Year Study
| Autor: | Hun Lee, Eung Kweon Kim, Tae Im Kim, Byoung Jin Ha, David Sung Yong Kang, Jin Young Choi, Kyoung Yul Seo |
|---|---|
| Rok vydání: | 2017 |
| Předmět: |
Adult
Male medicine.medical_specialty Visual acuity Distance visual acuity Ultraviolet Rays medicine.medical_treatment Corneal Stroma Riboflavin Corneal collagen cross-linking Visual Acuity Spherical equivalent Keratoconus Refraction Ocular Photorefractive Keratectomy 03 medical and health sciences Ocular physiology Young Adult 0302 clinical medicine Ophthalmology medicine Humans Manifest refraction Retrospective Studies Photosensitizing Agents medicine.diagnostic_test business.industry Epithelium Corneal Corneal Topography Corneal topography Combined Modality Therapy Photorefractive keratectomy Cross-Linking Reagents Treatment Outcome Photochemotherapy 030221 ophthalmology & optometry Female Lasers Excimer Collagen medicine.symptom business 030217 neurology & neurosurgery |
| Zdroj: | Cornea. 36(10) |
| ISSN: | 1536-4798 |
| Popis: | PURPOSE To investigate the effects of combined transepithelial photorefractive keratectomy (tPRK) and accelerated corneal collagen cross-linking (CXL) on visual acuity and refractive outcomes. METHODS The medical records of 89 eyes (89 patients) undergoing combined tPRK and CXL (tPRK-CXL group) or tPRK alone (tPRK group) were retrospectively analyzed. Uncorrected distance visual acuity (UDVA), corrected distance visual acuity, and manifest refraction spherical equivalent (MRSE) were evaluated preoperatively and 2 weeks, 1, 3, 6, and 12 months after surgery. RESULTS At 2 weeks after surgery, the tPRK-CXL group had better UDVA than the tPRK group (0.97 ± 0.22 vs. 0.85 ± 0.22, P = 0.015). At 2 weeks and 1 month after surgery, the tPRK-CXL group had a significantly lower spherical error than the tPRK group (0.24 vs. 0.63 D, P = 0.017, for 2 weeks and 0.43 vs. 0.57 D, P = 0.019, for 1 month). At 12 months after surgery, the tPRK-CXL group had a lower spherical error and MRSE than the tPRK group (0.30 vs. 0.44 D, P < 0.001, for the spherical error and 0.17 vs. 0.31 D, P < 0.001, for the MRSE). Both groups had comparable predictability, efficacy, and safety indices at 12 months after surgery. CONCLUSIONS Combined tPRK and accelerated CXL demonstrated comparable predictability, efficacy, and safety compared with tPRK alone. Combined tPRK and CXL provides better UDVA in the early postoperative period and better refractive outcomes at 12 months postoperatively in terms of spherical error and MRSE. |
| Databáze: | OpenAIRE |
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