Synthesis of New Chiral 4,5,6,7-Tetrahydro[1,2,3]triazolo[1,5-a]pyrazines from α-Amino Acid Derivatives under Mild Conditions

Autor:	Pradip K. Maity, Mukund K. Gurjar, Rajesh G. Gonnade, Mukund S. Chorghade, Debendra K. Mohapatra
Rok vydání:	2007
Předmět:	chemistry.chemical_classification 1 2 3-Triazole Pyrazine Organic Chemistry Triazole Regioselectivity General Medicine Combinatorial chemistry Amino acid Solvent chemistry.chemical_compound chemistry Intramolecular force 1 3-Dipolar cycloaddition Triazole derivatives Click chemistry Organic chemistry
Zdroj:	Synlett. 2007:1893-1896
ISSN:	1437-2096 0936-5214
DOI:	10.1055/s-2007-984537
Popis:	A practical and efficient regioselective synthesis of several new chiral 4,5,6,7-tetrahydro[1,2,3]triazolo[1,5-a]pyrazines is described from α -amino acid derivatives following intramolecular 'click' reaction as the key step. The method obviates product -purification; to obtain the pure triazole products, only the solvent needs to be evaporated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7bb3316a8bcfb04f45a438e52d01c2c https://doi.org/10.1055/s-2007-984537 Zobrazit plný text záznamu