Anti-S antibodies: an unusual cause of haemolytic disease of the fetus and newborn (HDFN)
| Autor: | Alan Finan, Oluwafemi Akinlabi, W Murphy, Azhar Syed, Christopher Pitan |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| Předmět: |
medicine.medical_specialty
Pediatrics medicine.medical_treatment Hepatosplenomegaly Exchange transfusion Protein S Article Erythroblastosis Fetal medicine Humans Autoantibodies Fetus biology Obstetrics business.industry Autoantibody Infant Newborn General Medicine Fetal movement biology.protein Female medicine.symptom Antibody business Haemolytic disease |
| Popis: | We report a case of haemolytic disease of the fetus and newborn due to anti-S antibodies. Baby G was born by emergency caesarean section at 35 weeks due to reduced fetal movement. Prior to delivery, antenatal screening revealed the mother9s blood group was AB rhesus positive with anti-S antibody titres. The baby was pale but non-hydropic at birth with hepatosplenomegaly. Haemoglobin at birth was 5.23 g/dl and serum bilirubin 138 µmol/l. The baby required phototherapy, γ-globulin infusion and exchange transfusion with post-transfusion complications. |
| Databáze: | OpenAIRE |
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