Lymphoepithelioma-like Carcinoma of Endometrium; A Rare Case Report
| Autor: | JH Makannavar, Jayaprakash K Shetty, Hosapatna L Kishanprasad |
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| Rok vydání: | 2015 |
| Předmět: |
Lymphoepithelioma-like carcinoma
Pathology medicine.medical_specialty business.industry Case Report Histology Endometrium medicine.disease Cytokeratin medicine.anatomical_structure Oncology Lymphoplasmacytic Infiltrate Surgical oncology hemic and lymphatic diseases medicine Endometrial Polyp Surgery business Lymphoepithelioma |
| Zdroj: | Indian Journal of Surgical Oncology. 6:130-134 |
| ISSN: | 0976-6952 0975-7651 |
| Popis: | Lymphoepithelioma –like carcinomas (LELCs) are tumors with histological features similar to those of lymphoepithelioma of nasopharynx. They have been described in many organs including female genital tract. Their histology is characterized by sheets, nests and cords of large syncytial tumor cells containing round nuclei with prominent nucleoli and dense lymphoplasmacytic infiltrate in the stoma. The association of Epstein-Barr virus (EBV) with LELCs has not been observed in western patients. But a few Asian patients with these tumors in uterine cervix have shown positive association of EBV. Cervical LELCs harbor EBV more frequently than cervical squamous cell carcinomas. These tumors are rarer in endometrium. Only 3 cases have been reported and the association of EBV has not been observed. We present here a rare case of LELC in endometrial polyp from India, who presented with postmenopausal vaginal bleeding. The tumor cells were positive for cytokeratin and EBV Latent membrane protein-1. |
| Databáze: | OpenAIRE |
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