Aortitis syndrome (Takayasu's arteritis) with cataract and elevated serum level of vascular endothelial growth factor

Autor: Eiko Ikeda, Masaharu Sakamoto, Hiroshi Yoshida, Hiroyuki Koga, Shotaro Sakisaka, Yasuo Teshima, Michio Sata, Kyuichi Tanikawa, Masaru Harada, Keiichi Mitsuyama, Matsuo Katsuhiko
Rok vydání: 1998
Předmět:
Zdroj: Scandinavian journal of rheumatology. 27(1)
ISSN: 0300-9742
Popis: The aortitis syndrome is a chronic inflammatory process that affects the aorta and its primary branches. Patients with aortitis syndrome exhibit various ocular changes. We present a patient in whom cataract was the initial objective finding. The serum concentration of vascular endothelial growth factor, a cytokine that affects neovascularization, and vasopermeability, was elevated before the initiation of prednisolone treatment. Cataract should be considered as a possible characteristic initial finding in patients with aortitis syndrome. Vascular endothelial growth factor may be involved in the progression of aortitis syndrome.
Databáze: OpenAIRE