Impact of admission anemia, C-reactive protein and mean platelet volume on short term mortality in patients with acute ST-elevation myocardial infarction treated with primary angioplasty
| Autor: | Zdravko Babić, Hrvoje Pintarić, Mislav Vrsalovic, Marin Pavlov, Vjeran Nikolić Heitzler, Nada Vrkić, Biserka Getaldić, Ana Vrsalović Presečki |
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| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Blood Platelets
Male Risk medicine.medical_specialty anemia C-reactive protein mean platelet volume mortality myocardial infarction Anemia Clinical Biochemistry Myocardial Infarction Patient Admission Internal medicine Humans Medicine Myocardial infarction Angioplasty Balloon Coronary Mean platelet volume Aged Cell Size Aged 80 and over Framingham Risk Score biology business.industry General Medicine Odds ratio Middle Aged Prognosis medicine.disease Survival Analysis Confidence interval C-Reactive Protein ROC Curve Multivariate Analysis Cardiology biology.protein Female Hemoglobin business |
| Popis: | Objectives To investigate admission anemia, C-reactive protein (CRP) and mean platelet volume (MPV) together as prognostic markers in ST-elevation myocardial infarction (STEMI). Design and methods Baseline hemoglobin, CRP and MPV were determined in 543 patients with acute STEMI to whom primary angioplasty was performed and evaluated for short term mortality (30 days). Results After multivariate analysis anemia (odds ratio 2.69, 95% confidence interval 1.24–5.86) and CRP (odds ratio 3.40, 95% confidence interval 1.13–10.22) remained significant independent predictors of short-term mortality. Addition of anemia and CRP to PAMI risk score improved prediction of short-term outcome; area under ROC curve rose from 0.76 to 0.87 (p Conclusion Better ability to determine 30-day mortality was obtained when anemia and CRP were incorporated into the PAMI risk score. |
| Databáze: | OpenAIRE |
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