Comparative Analysis of Simultaneous Transcranial Doppler and Perfusion Computed Tomography for Cerebral Perfusion Evaluation in Patients with Traumatic Brain Injury
| Autor: | Anatoly Sheludyakov, Denis E. Bragin, Kseniia Trofimova, Darya Agarkova, Michael Dobrzeniecki, Dmitry Martynov, Artem Kopylov, Alex Trofimov |
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| Rok vydání: | 2020 |
| Předmět: |
Middle Cerebral Artery
medicine.medical_specialty Ultrasonography Doppler Transcranial Traumatic brain injury Intracranial hematoma Cerebral arteries Article 03 medical and health sciences Cerebral circulation 0302 clinical medicine Internal medicine Brain Injuries Traumatic Humans Medicine 030212 general & internal medicine Cerebral perfusion pressure business.industry medicine.disease Transcranial Doppler Cerebral blood flow Cerebrovascular Circulation Cardiology Tomography X-Ray Computed business Perfusion Blood Flow Velocity |
| Zdroj: | Advances in Experimental Medicine and Biology ISBN: 9783030344597 Adv Exp Med Biol |
| DOI: | 10.1007/978-3-030-34461-0_8 |
| Popis: | The aim was to investigate the feasibility of simultaneous comparison of cerebral circulation in major vessels and microvasculature in patients suffering traumatic brain injury (TBI) with or without intracranial hematomas (IH). Methods. 170 patients were divided into two groups: Group 1 – diffuse TBI (75 patients); and Group 2 – TBI with IH (95 patients: 18 epidural, 65 subdural and 12 multiple). Perfusion computed tomography (PCT) for assessment of volumetric cerebral blood flow (CBF) was done 2–15 days after admission to hospital. Simultaneous assessment of cerebral blood flow velocity (CBFV) in both middle cerebral arteries was done by transcranial Doppler. Results. In patients with diffuse TBI, CBF had statistically valid correlations with CBFV (r = 0.28, p = 0.0149 on the left side; r = 0.382, p = 0.00075 on the right side). In patients with TBI and IH, the analysis did not reveal any reliable correlations between the CBFV and CBF velocity in the temporal lobes, either on the side of the removed IH or on the opposite side. Conclusion. The greatest linear correlation was noted in patients with diffuse TBI without the development of a coarse shift of the midline structures and dislocation syndrome. This correlation decreases with the increase in injury severity and development of secondary complications in the acute period, which probably reflects impairment of the coupling of oxygen consumption by brain tissue and cerebral microcirculation. |
| Databáze: | OpenAIRE |
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