Hieracium waldsteinii (Asteraceae) and Onosma stellulata (Boraginaceae) as a Source of Antioxidant and Antimicrobial Agents
| Autor: | Kostić Aleksandar Ž., Mačukanović-Jocić , Marina P, Milinčić Danijel D, Petrović Jovana D, Gašič, Uroš M, Gligorijević Nevenka N, Jarić, Snežana V., Soković, Marina D., Tešić, Živoslav Lj., Pešić, Mirjana B. |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
antimicrobial activity
Plant Extracts Bioengineering General Chemistry General Medicine Asteraceae Boraginaceae Hieracium waldsteini Biochemistry antioxidant properties Antioxidants Anti-Bacterial Agents Onosma stellulata Phenols Molecular Medicine Molecular Biology Hieracium waldsteinii phenolic composition |
| Zdroj: | Chemistry and Biodiversity |
| Popis: | The current study aimed to phytochemically characterize (including a detailed phenolic profile) two endemic Balkan's species (Hieracium waldsteinii and Onosma stellulata) and determine their possible application as a source of natural antioxidant and antimicrobial agents. The main phenolic compound in both species (in all examined parts) was chlorogenic acid. Eriodictyol, genistein and naringenin were quantified only in H. waldsteinii while isorhamnetin-3-O-rutinoside and sinapic acid were characteristic for O. stellulata. The highest antioxidant activity (98 mg AAE/g dry weight for TAC assay) was ascribed to the flower extract of H. waldsteinii while the lowest results (∼4.3 mg AAE/g dry weight for FRP assay) were exhibited by the extracts obtained from the plant's stem. Antimicrobial assays showed moderate antibacterial, i. e., moderate/strong activity against several tested fungi (in particular Trichoderma viride). Correlation analysis revealed strong positive connection between phenolic compounds and reducing power of extracts as well as between total phenolic and flavonoid content and the obtained minimal inhibitory concentration recorded in antibacterial assays. |
| Databáze: | OpenAIRE |
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