Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017

Autor: Maria Teresa Della Rocca, Colombina Melardo, Roberta Astorri, Mariateresa Vitiello, Emiliana Finamore, Gianluigi Franci, Annalisa Chianese, Massimiliano Galdiero, Francesco Bencivenga, Valeria Crudele, Emilia Galdiero
Přispěvatelé: Franci, G., Crudele, V., Della Rocca, M. T., Melardo, C., Chianese, A., Finamore, E., Bencivenga, F., Astorri, R., Vitiello, M., Galdiero, E., Galdiero, M.
Rok vydání: 2019
Předmět:
Male
Epstein-Barr Virus Infections
Herpesvirus 4
Human
Pediatrics
Mononucleosis
Antibodies
Viral
medicine.disease_cause
Hospitals
University
Epstein-Barr Virus Infection
Retrospective Studie
Seroepidemiologic Studies
hemic and lymphatic diseases
Prevalence
Asymptomatic Infection
Age Factor
Child
Asymptomatic Infections
Aged
80 and over
Age Factors
Epstein-Barr viru
Middle Aged
University hospital
Infectious Diseases
Italy
Child
Preschool
Female
medicine.symptom
Human
Adult
medicine.medical_specialty
IgM
Adolescent
IgG
Lymphoproliferative disorders
Asymptomatic
Virus
Young Adult
Primary infection
Virology
medicine
Humans
Seroprevalence
Aged
Retrospective Studies
business.industry
Seroepidemiologic Studie
Significant difference
Infant
Newborn
Infant
medicine.disease
EBV nuclear antigen
Epstein–Barr virus
business
Zdroj: Intervirology. 62:15-22
ISSN: 1423-0100
0300-5526
Popis: Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in “Luigi Vanvitelli” University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection.
Databáze: OpenAIRE
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