Epstein-Barr Virus Seroprevalence and Primary Infection at the University Hospital Luigi Vanvitelli of Naples from 2007 to 2017
| Autor: | Maria Teresa Della Rocca, Colombina Melardo, Roberta Astorri, Mariateresa Vitiello, Emiliana Finamore, Gianluigi Franci, Annalisa Chianese, Massimiliano Galdiero, Francesco Bencivenga, Valeria Crudele, Emilia Galdiero |
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| Přispěvatelé: | Franci, G., Crudele, V., Della Rocca, M. T., Melardo, C., Chianese, A., Finamore, E., Bencivenga, F., Astorri, R., Vitiello, M., Galdiero, E., Galdiero, M. |
| Rok vydání: | 2019 |
| Předmět: |
Male
Epstein-Barr Virus Infections Herpesvirus 4 Human Pediatrics Mononucleosis Antibodies Viral medicine.disease_cause Hospitals University Epstein-Barr Virus Infection Retrospective Studie Seroepidemiologic Studies hemic and lymphatic diseases Prevalence Asymptomatic Infection Age Factor Child Asymptomatic Infections Aged 80 and over Age Factors Epstein-Barr viru Middle Aged University hospital Infectious Diseases Italy Child Preschool Female medicine.symptom Human Adult medicine.medical_specialty IgM Adolescent IgG Lymphoproliferative disorders Asymptomatic Virus Young Adult Primary infection Virology medicine Humans Seroprevalence Aged Retrospective Studies business.industry Seroepidemiologic Studie Significant difference Infant Newborn Infant medicine.disease EBV nuclear antigen Epstein–Barr virus business |
| Zdroj: | Intervirology. 62:15-22 |
| ISSN: | 1423-0100 0300-5526 |
| Popis: | Epstein-Barr virus (EBV) is a common herpesvirus that may cause asymptomatic infection or various diseases, such as mononucleosis, lymphoproliferative disorders and several cancers. Our objective was to estimate the prevalence of EBV among patients hospitalized in “Luigi Vanvitelli” University Hospital in the last 10 years. Our results showed that EBV seroprevalence in our geographical area was 65%. Seroprevalence increased gradually with age with no significant difference between females (49.42%) and males (50.58%). The seropositivity for primary infection was higher in patients about 5 years old, while seropositivity for past infection was predominant in patients of about 35 years old. These results underline that children in our country are still exposed to EBV. The development and the deeper use of an EBV vaccine in the early years of life could represent the solution for this infection. |
| Databáze: | OpenAIRE |
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