Paroxysmal atrial fibrillation prevention by pacing in patients with pacemaker indication
| Autor: | J. J. Manzano, J. Toquero, J. M. M. Ferrer, J. Roda, F. Andrade, R. Ceres, Ignacio Fernández Lozano, M. Méndez, J. Errejon, A. Vincent |
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| Rok vydání: | 2003 |
| Předmět: |
Male
medicine.medical_specialty Pacemaker Artificial Paroxysmal atrial fibrillation Sick sinus syndrome Physiology (medical) Internal medicine Atrial Fibrillation medicine Humans In patient Clinical significance Prospective Studies Registries Aged Fibrillation Aged 80 and over Sick Sinus Syndrome Atrial pacing business.industry Cardiac Pacing Artificial Atrial fibrillation Middle Aged medicine.disease SSS Cardiology Female medicine.symptom Cardiology and Cardiovascular Medicine business Algorithms |
| Zdroj: | Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 5(3) |
| ISSN: | 1099-5129 |
| Popis: | Aims The prevent-atrial fibrillation (AF) registry analyses the clinical relevance and usefulness of the four preventive pacing algorithms, available in a family of cardiac stimulators, to prevent atrial fibrillation. Methods and Results This study is a prospective, non-randomized, multicentre registry. Patients are eligible for the registry if they have sick sinus syndrome (SSS) with or without pre-existing atrial fibrillation. The preventive pacing algorithms were programmed for each patient on an individual basis using the diagnostic features of the devices. In the period from April 2000 to April 2001 a total of 68 patients (33 male, 35 female) has been included in the registry in 14 hospitals in Spain. Mean age was 72±12 years and the pacemaker indication was SSS in 15 patients (22%) and SSS with paroxysmal AF in 53 patients (78%). The median AF burden for the total group (n=32) was significantly reduced from 3.9 to 1.3% (67%, P =0.034, Wilcoxon signed rank test). The decrease in AF burden was accompanied by a non-significant decrease in the median number of episodes per day from 1.47 to 0.64 (a decrease of 56%). The average atrial pacing % was increased from 72 to 78%. Conclusions The prevent-AF registry demonstrated the usefulness of four preventive pacing algorithms in daily clinical practice. During the registry a significant reduction in AF burden and all other endpoints was observed. Dedicated diagnostics were key to adapting the optimal pacing therapy during follow-up. |
| Databáze: | OpenAIRE |
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