Age-Specific Prevalence of Antibody to Enterotoxigenic Escherichia coli in Ecuadorian and German Children
| Autor: | Harriet Link, Denis Barclay, Josette Sidoti, Wilma B. Freire, Harald Brüssow, Yen K. Hoang, H. Dirren |
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| Rok vydání: | 1990 |
| Předmět: |
Diarrhea
Lipopolysaccharides Bacterial Toxins Enzyme-Linked Immunosorbent Assay Enterotoxin Biology medicine.disease_cause Microbiology Enterotoxins Enterotoxigenic Escherichia coli Escherichia coli Prevalence medicine Humans Immunology and Allergy Escherichia coli Infections Escherichia coli Proteins Age Factors Germany West Antibody titer Infant bacterial infections and mycoses Antibodies Bacterial Titer Infectious Diseases Child Preschool Immunoglobulin G Diarrhea Infantile Humoral immunity Immunology biology.protein Ecuador medicine.symptom Antibody |
| Zdroj: | Journal of Infectious Diseases. 162:974-977 |
| ISSN: | 1537-6613 0022-1899 |
| DOI: | 10.1093/infdis/162.4.974 |
| Popis: | Serum samples from 1397 Ecuadorian children 0-5 years of age were tested by ELISA for antibodies to enterotoxigenic Escherichia coli (ETEC). A gradual prevalence and titer increase was seen for IgG antibodies to heat-labile enterotoxin in children 6-18 months old; 90% prevalences were reached in the second year of life. At this age less than 10% of West German children showed IgG antibodies to heat-labile enterotoxin. In Ecuador age-related ETEC-specific antibody titer increases correlated with age-related prevalence of diarrheal disease. On the other hand, pooled lipopolysaccharide from different ETEC-associated O serogroups could not be used as a seroepidemiologic marker of ETEC infections. |
| Databáze: | OpenAIRE |
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