N-Heterocyclic Carbene-Catalyzed Asymmetric Synthesis of Cyclopentenones

Autor:	Bolai Chen, Xiangwen Kong, Chenglin Ding, Benlong Luo, Jinggong Liu, Shuang Yang, Zhizhou Chen, Shengtong Niu, Changyu Zhou, Xinqiang Fang
Rok vydání:	2021
Předmět:	010405 organic chemistry Chemistry Organic Chemistry Enantioselective synthesis 010402 general chemistry 01 natural sciences Biochemistry Combinatorial chemistry 0104 chemical sciences Catalysis chemistry.chemical_compound Molecule Physical and Theoretical Chemistry Carbene
Zdroj:	Organic Letters. 23:3403-3408
ISSN:	1523-7052 1523-7060
DOI:	10.1021/acs.orglett.1c00870
Popis:	N-Heterocyclic carbene-catalyzed asymmetric construction of cyclopentenones using enals and α-diketones is achieved, furnishing a series of highly functionalized cyclopentenones in a highly diastereo- and enantioselective manner. The protocol tolerates substrates with both aromatic and aliphatic groups, and further transformations of the products delivered a range of value-added molecules.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c754248b700a2849266004f8ea48f756 https://doi.org/10.1021/acs.orglett.1c00870 Zobrazit plný text záznamu