Oral rehydration solution normalizes plasma renin and aldosterone levels in patients with ulcerative colitis after proctocolectomy
| Autor: | Chikashi Shibata, Munenori Nagao, Sho Haneda, Michiaki Unno, Y. Funayama, Kouhei Fukushima, Katsuyoshi Kudoh, Kazuhiro Watanabe, Takeshi Naitoh, Kenichi Takahashi |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Aldosterone business.industry Proctocolectomy medicine.medical_treatment oral rehydration solution Urine Anastomosis medicine.disease Gastroenterology Plasma renin activity Ulcerative colitis Excretion chemistry.chemical_compound Endocrinology chemistry after proctocolectomy Internal medicine Renin–angiotensin system medicine lcsh:Diseases of the digestive system. Gastroenterology Original Research Article lcsh:RC799-869 business ulcerative colitis |
| Zdroj: | Journal of the Anus, Rectum and Colon, Vol 1, Iss 3, Pp 78-83 (2017) Journal of the Anus, Rectum and Colon |
| ISSN: | 2432-3853 |
| Popis: | Objectives The possible effects and benefits of oral rehydration solution (ORS) on chronic dehydration after total proctocolectomy. Methods To evaluate the effect of ORS on the renin-angiotensin system after remnant proctocolectomy in patients with ulcerative colitis (UC), we selected 20 patients after remnant proctocolectomy, ileal J pouch-anal anastomosis, and construction of a diverting ileostomy for UC. Patients were randomly divided into two groups, A (n=9) or B (n=11), 2 weeks after the surgery. In group A, ORS (1000 mL/day) was given for the first 7 days and mineral water (1000 mL/day) for the next 7 days. In group B, mineral water (1000 mL/day) was given for the first 7 days and ORS (1000 mL/day) for next 7 days. Plasma levels of renin, aldosterone and excretion of sodium in urine were evaluated at days 0, 7, and 14. We defined day 0 as the day of beginning this study. Results Mean plasma renin levels on day 0 were six to eight times greater than the upper normal limit. In group A, ORS lowered plasma renin levels. In group B, plasma levels of renin and aldosterone after ORS were lower than those at days 0 and 7. Conclusions ORS corrected increased plasma levels of renin and aldosterone to within the normal range in patients after proctocolectomy. |
| Databáze: | OpenAIRE |
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