Effect of Lipids on Insulin, Growth Hormone and Exocrine Pancreatic Secretion in Man
| Autor: | Sotirios Raptis, U. Klör, J. Kissing, H.C. Dollinger, Ernst-Friedrich Pfeiffer, K. E. Schröder, Ludwig von Berger |
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| Rok vydání: | 1975 |
| Předmět: |
Blood Glucose
Glycerol medicine.medical_specialty Bilirubin medicine.medical_treatment Clinical Biochemistry Blood sugar Fatty Acids Nonesterified Biochemistry chemistry.chemical_compound Gastric inhibitory polypeptide Pancreatic Juice Internal medicine Insulin Secretion medicine Humans Insulin Trypsin Secretion Triglycerides Triglyceride General Medicine Lipids Growth hormone secretion Endocrinology chemistry Growth Hormone Cholecystokinin medicine.drug |
| Zdroj: | European Journal of Clinical Investigation. 5:521-526 |
| ISSN: | 1365-2362 0014-2972 |
| DOI: | 10.1111/j.1365-2362.1975.tb00485.x |
| Popis: | Influences of fat on release of insulin, growth hormone and pancreatic enzyme secretion were studied in 35 metabolically healthy subjects. A fat solution containing 40 g of soy bean oil was administered, I. V., orally and intraduodenally. In all cases there was a similar increase of insulin but the rise in serum insulin after oral or intraduodenal fat administration was not related to the changes in plasma free fatty acids, free glycerol and triglyceride levels. Blood sugar responded according to insulin secretion. The route of fat administration may possibly influence growth hormone secretion. Following intraduodenal fat administration volume and bicarbonate contents of the duodenal juice rose slightly whereas trypsin and bilirubin content increased considerably. These results suggest that insulin secretion after oral or intraduodenal administration of fat is influenced by intestinal factors. Cholecystokinin-pancreozymin and gastric inhibitory polypeptide are qualified to serve as such factors. |
| Databáze: | OpenAIRE |
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