Multidisciplinary Approach in the Early Detection of Undiagnosed Connective Tissue Diseases in Patients With Interstitial Lung Disease: A Retrospective Cohort Study
| Autor: | Francesca Mariani, Emiliano Marasco, Claudio Tirelli, Carlo Alberto Scirè, Veronica Codullo, Adele Valentini, Tiberio Oggionni, Claudia Alpini, Valentina Morandi, Federica Meloni, Zamir Kadija, Ludovico De Stefano, Claudia La Carrubba, Andrea Franconeri, Carlomaurizio Montecucco, Lorenzo Cavagna, Giovanni Zanframundo, Silvia Grignaschi, Roberto Dore, Patrizia Morbini |
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| Přispěvatelé: | Tirelli, C, Morandi, V, Valentini, A, La Carrubba, C, Dore, R, Zanframundo, G, Morbini, P, Grignaschi, S, Franconeri, A, Oggionni, T, Marasco, E, De Stefano, L, Kadija, Z, Mariani, F, Codullo, V, Alpini, C, Scire, C, Montecucco, C, Meloni, F, Cavagna, L |
| Jazyk: | angličtina |
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
rheumatology Context (language use) behavioral disciplines and activities NO early diagnosis rheumatology interstitial lung disease multidisciplinary team pulmonology radiology connective tissue diseases 03 medical and health sciences 0302 clinical medicine Internal medicine Medicine Intensive care medicine multidisciplinary team pulmonology Original Research 030203 arthritis & rheumatology interstitial lung disease lcsh:R5-920 Lung business.industry Interstitial lung disease Retrospective cohort study General Medicine respiratory system medicine.disease Connective tissue disease Rheumatology radiology respiratory tract diseases body regions Pulmonology medicine.anatomical_structure 030228 respiratory system connective tissue disease early diagnosi CTD connective tissue diseases lcsh:Medicine (General) business early diagnosis |
| Zdroj: | Frontiers in Medicine Frontiers in Medicine, Vol 7 (2020) |
| ISSN: | 2296-858X |
| Popis: | Interstitial lung disease (ILD) encompasses a wide range of parenchymal lung pathologies with different clinical, histological, radiological, and serological features. Follow-up, treatment, and prognosis are strongly influenced by the underlying pathogenesis. Considering that an ILD may complicate the course of any connective tissue disease (CTD) and that CTD's signs are not always easily identifiable, it could be useful to screen every ILD patient for a possible CTD. The recent definition of interstitial pneumonia with autoimmune features is a further confirmation of the close relationship between CTD and ILD. In this context, the multidisciplinary approach is assuming a growing and accepted role in the correct diagnosis and follow-up, to as early as possible define the best therapeutic strategy. However, despite clinical advantages, until now, the pathways of the multidisciplinary approach in ILD patients are largely heterogeneous across different centers and the best strategy to apply is still to be established and validated. Aims of this article are to describe the organization of our multidisciplinary group for ILD, which is mainly focused on the early identification and management of CTD in patients with ILD and to show our results in a 1 year period of observation. We found that 15% of patients referred for ILD had an underlying CTD, 33% had interstitial pneumonia with autoimmune feature, and 52% had ILD without detectable CTD. Furthermore, we demonstrated that the adoption of a standardized strategy consisting of a screening questionnaire, specific laboratory tests, and nailfold videocapillaroscopy in all incident ILD proved useful in making the right diagnosis. |
| Databáze: | OpenAIRE |
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