Catheter related sepsis during long-term parenteral nutrition in paediatric gastroenterology patients: a study of 185 consecutive central venous catheters
| Autor: | Dominique Jan, Claude Ricour, Descamps P, M. Larchet, Yann Revillon, Stephen Lortat-Jacob, V. Goulet, Jean-Louis Gaillard, Olivier Goulet |
|---|---|
| Rok vydání: | 1990 |
| Předmět: |
Resuscitation
medicine.medical_specialty Nutrition and Dietetics business.industry Incidence (epidemiology) Critical Care and Intensive Care Medicine medicine.disease Surgery Sepsis Catheter Parenteral nutrition El Niño otorhinolaryngologic diseases Medicine business Complication Prospective cohort study |
| Zdroj: | Clinical Nutrition. 9:73-78 |
| ISSN: | 0261-5614 |
| DOI: | 10.1016/0261-5614(90)90056-x |
| Popis: | We report the results of a prospective study of catheter-related sepsis (CRS) in 154 gastroenterology paediatric patients treated for medical (n = 102) or surgical (n = 52) disorders. Over 2 years, 185 central venous catheters (CVC) were placed, including 155 Broviac and 30 Jonathan Shaw CVC. CVC remained in place 13,331 days (6,539 days of cyclic parenteral nutrition), with a mean catheter life of 72 days. Forty-eight episodes of CRS occurred, most of them due to coagulase-negative staphylococci (n = 29) and Staphylococcus aureus (n = 17). CRS rate was 0.26, with an overall incidence of 1 infection per 278 days of parenteral nutrition (PN). Factors significantly associated with CRS were: age 1–5 years (p < 0.01), a medical indication for treatment (p < 0.001) and summer months of PN (p < 0.01). Interestingly, CRS occurred predominantly (65%) within the first 2 months following CVC placement and the risk of infection correlated with local haemorrhage at the time of insertion (p < 0.01). Appropriate systemic therapy, without removing the catheter, permitted resolution of 90.9% (4044) of all CRS and 100% (2828) of CRS due to coagulase-negative staphylococci. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|