Seasonal changes in indoor airborne fungal concentration in a hematology ward
| Autor: | Taku Kikuchi, Jun Kato, Takehiko Mori, Mitsuru Murata, Rie Yamazaki, Osamu Kikumi, Shinichiro Okamoto, Masatoshi Sakurai, Yuya Koda, Hitomi Nakayama, Naoki Hasegawa, Rika Inose |
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| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
Microbiology (medical) Hematological disorders medicine.medical_specialty Veterinary medicine 030106 microbiology Air Microbiology Colony Count Microbial Air sampler Biology 03 medical and health sciences 0302 clinical medicine Japan Infectious complication Internal medicine medicine Humans Pharmacology (medical) 030212 general & internal medicine Air filter Hematology Incidence (epidemiology) Penicillium Hospitals Infectious Diseases Invasive fungal disease Aspergillus Fungal Counts Seasons Cladosporium Immunocompetence Invasive Fungal Infections |
| Zdroj: | Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy. 26(4) |
| ISSN: | 1437-7780 |
| Popis: | Invasive fungal disease (IFD) is an important infectious complication of hematological disorders, especially in hematopoietic stem cell transplantation recipients. Evidences suggest seasonal and/or geographical variations in the airborne fungal counts and a relationship between those counts and the incidence of IFD. We evaluated the concentrations of indoor airborne fungi quantitated over the course of one year in a hematology ward in Japan. In January, April, July, and October, fixed volumes of air samples were obtained by an air sampler in a hematology ward not equipped with a high-efficiency particulate air filter and incubated in fugal cultures. Samples were also obtained from a protective environment in the same ward and were evaluated. The number of fungal colonies per 50 L of sampled air was highest in October (median 2.25 (range, 0.2-7.0)), which was significantly higher than those in the other three months (0.1 (range, 0-1.0) in January; 0 (0-0) in April; 0.55 (0-2.5) in July; P 0.01)). Commonly identified pathogens included Penicillium and Cladosrporium species, but Aspergillus species was detected only in July and October samples. These results suggest a seasonal variation in indoor airborne fungal concentrations in Japan, which could affect the epidemiology of IFD. |
| Databáze: | OpenAIRE |
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