Amphotericin B-induced dilated cardiomyopathy

Autor: Yahya Ismail, Karunakar, Edward L. Arsura, Sheldon I. Freedman
Rok vydání: 1994
Předmět:
Zdroj: The American journal of medicine. 97(6)
ISSN: 0002-9343
Popis: A mphotericin B remains the standard treatment for serious mycotic infections such as coccidioidomycosisl Amphotericin B is associated with several notable complications such as nephrotoxicity,2 anemia, fever, and ~hills.~ Lethal complications, such as pulmonary decompensation4 and ventricular fibrillation,5 have rarely been reported. Myocardial dysfunction secondary to amphotericin B has never been previously described. In this report we describe a patient who, while receiving amphotericin B for disseminated coccidioidomycosis, developed dilated cardiomyopathy with clinical congestive heart failure. Cardiac dysfunction reversed after treatment with amphotericin B was terminated.
Databáze: OpenAIRE