The Role of Knowledge and Attitudes About Nonsteroidal Anti‐inflammatory Drugs in Determining Treatment Use
| Autor: | Jazmin Dagnino, M. J. Hannon, Cristian Quinones, Said A. Ibrahim, L. R. M. Hausmann, Ernest R. Vina, C.K. Kwoh |
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| Rok vydání: | 2021 |
| Předmět: |
musculoskeletal diseases
medicine.medical_specialty lcsh:Diseases of the musculoskeletal system Nonsteroidal Clinical variables business.industry Original Articles Osteoarthritis Treatment use medicine.disease digestive system digestive system diseases Confidence interval Risk perception chemistry.chemical_compound Rheumatology chemistry Relative risk Internal medicine Medicine Original Article lcsh:RC925-935 Medical prescription skin and connective tissue diseases business |
| Zdroj: | ACR Open Rheumatology ACR Open Rheumatology, Vol 3, Iss 3, Pp 154-163 (2021) |
| ISSN: | 2578-5745 |
| Popis: | Objective The objective of this study was to evaluate how patient knowledge and beliefs regarding nonsteroidal anti‐inflammatory drugs (NSAIDs) may influence the use of NSAIDs for osteoarthritis (OA). Methods Surveys of 334 adults with knee and/or hip OA were analyzed in this cross‐sectional study. Familiarity with and perceptions of benefits/risks of NSAID use were measured to assess associations with the use of prescription and nonprescription oral NSAIDs. Multinomial logistic regression models were adjusted for sociodemographic and clinical variables. Results In this sample, 35.9% and 35.6% reported use of oral prescription and nonprescription‐only NSAIDs, respectively. Hispanic participants, compared with non‐Hispanic White participants, had lower perceived benefit (P = 0.005) and risk (P = 0.001) of prescription NSAIDs. The following were associated with prescription NSAID use instead of no NSAID use: having family/friends who used prescription (relative risk ratio [RRR] 3.91; 95% confidence interval [CI] 2.05‐7.47) and over‐the‐counter (OTC) (RRR 3.10; 95% CI 1.65‐5.83) NSAIDs for OA, understanding the consequences of using both prescription (RRR 3.50; 95% CI 1.79‐6.86) and OTC (RRR 2.80; 95% CI 1.39‐5.65) NSAIDs, higher perceived benefit of both prescription (RRR 2.51; 95% CI 1.71‐3.66) and OTC (RRR 1.44; 95% CI 1.01‐2.06) NSAIDs, and lower perceived risk of both types of NSAIDs (prescription: RRR 0.63 [95% CI 0.46‐0.87]; OTC: RRR 0.53 [95% CI 0.37‐0.75]). Similar results were found when we assessed the relationship between these variables and OTC NSAID use versus no oral NSAID use. Conclusion Adults with knee and/or hip OA were more likely to use NSAIDs if they were more familiar with, had an increased perceived benefit of, and had a decreased perceived risk of these drugs. Patients’ perceptions and beliefs about NSAIDs should be evaluated when considering them for treatment. |
| Databáze: | OpenAIRE |
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