Progression rate to primary angle closure following laser peripheral iridotomy in primary angle-closure suspects: a randomised study
| Autor: | Yi Peng, Ravi Thomas, Yuanbo Liang, Dapeng Mou, Sujie Fan, Ningli Wang |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Intraocular pressure
medicine.medical_specialty genetic structures Glaucoma Goldmann applanation tonometry Clinical Research Ophthalmology medicine Gonioscopy Synechia primary angle-closure suspects anterior chamber angle medicine.diagnostic_test business.industry RE1-994 medicine.disease eye diseases laser peripheral iridotomy medicine.anatomical_structure Laser peripheral iridotomy Progression rate Trabecular meshwork sense organs business intraocular pressure |
| Zdroj: | Int J Ophthalmol International Journal of Ophthalmology, Vol 14, Iss 8, Pp 1179-1184 (2021) |
| ISSN: | 2222-3959 |
| Popis: | AIM: To report the progression rate (PR) to primary angle closure (PAC) following laser peripheral iridotomy (LPI) in PAC suspects (PACS). METHODS: Prospective, randomized controlled interventional clinical trial conducted at the Handan Eye Hospital, China. Totally 134 bilateral PACS, defined as non-visibility of the posterior trabecular meshwork for ≥180 degrees on gonioscopy were randomly assigned to undergo LPI in one eye. Gonioscopy and Goldmann applanation tonometry were performed prior to, on day 7 and 12mo post LPI. RESULTS: Eighty of 134 patients (59.7%) could be followed up at one year. The mean intraocular pressure (IOP) in treated eyes was 15.9±2.6 mm Hg at baseline, 15.4±3.0 mm Hg on day 7; 16.5±2.9 mm Hg at one month, and 15.5±2.9 mm Hg at 12mo; the IOP in untreated eyes was similar (P=0.834). One or more quadrants of the angle opened in 93.7% of the LPI treated eyes, but 67.0% (53/79) remained closed in two or more quadrants. The PR to PAC in untreated eyes was 3.75% and one developed acute angle-closure glaucoma (AACG); the PR to PAC in treated eyes was 2.5% and none had developed peripheral anterior synechia (PAS) or AACG. CONCLUSION: LPI can open some of the occludable angle in the majority of eyes with PACS, but 67% continue to have non-visibility of the trabecular meshwork for over 180 degrees. |
| Databáze: | OpenAIRE |
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