Cancer diagnostic profile in children with structural birth defects: An assessment in 15,000 childhood cancer cases
| Autor: | Philip J. Lupo, Sonja A. Rasmussen, Tania A Desrosiers, Tiffany M. Chambers, Jeremy M. Schraw, Wendy N. Nembhard, Peter H. Langlois, Robert E. Meyer, Mark A. Canfield, Sharon E. Plon, Logan G. Spector |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Hepatoblastoma
Male Ependymoma Cancer Research Pediatrics medicine.medical_specialty Adolescent Population Article Congenital Abnormalities Causes of cancer Neuroblastoma 03 medical and health sciences 0302 clinical medicine Risk Factors Neoplasms Epidemiology of cancer Epidemiology medicine Humans Registries 030212 general & internal medicine Child education education.field_of_study business.industry Liver Neoplasms Infant Newborn Infant Cancer medicine.disease United States Oncology Child Preschool Hematologic Neoplasms 030220 oncology & carcinogenesis Female Germ cell tumors business |
| Zdroj: | Cancer |
| ISSN: | 1097-0142 0008-543X |
| Popis: | BACKGROUND Birth defects are established risk factors for childhood cancer. Nonetheless, cancer epidemiology in children with birth defects is not well characterized. METHODS Using data from population-based registries in 4 US states, this study compared children with cancer but no birth defects (n = 13,111) with children with cancer and 1 or more nonsyndromic birth defects (n = 1616). The objective was to evaluate cancer diagnostic characteristics, including tumor type, age at diagnosis, and stage at diagnosis. RESULTS Compared with the general population of children with cancer, children with birth defects were diagnosed with more embryonal tumors (26.6% vs 18.7%; q |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text