An Examination System to Detect Deep Vein Thrombosis of a Lower Limb Using Light Reflection Rheography

Autor: Kuo-Li Pan, Wenxi Chen, Chun-Hung Su, Shing-Hong Liu, Jia-Jung Wang
Jazyk: angličtina
Rok vydání: 2021
Předmět:
medicine.medical_specialty
Deep vein
0206 medical engineering
wearable device
02 engineering and technology
030204 cardiovascular system & hematology
lcsh:Chemical technology
Biochemistry
Article
Lower limb
deep vein thrombosis
Veins
Analytical Chemistry
03 medical and health sciences
0302 clinical medicine
Embolus
Pregnancy
Internal medicine
Photoplethysmogram
medicine
Humans
lcsh:TP1-1185
cardiovascular diseases
Electrical and Electronic Engineering
Instrumentation
Aged
Light reflection rheography
Venous Thrombosis
light reflection rheography
Receiver operating characteristic
business.industry
medicine.disease
020601 biomedical engineering
Thrombosis
Atomic and Molecular Physics
and Optics

medicine.anatomical_structure
Lower Extremity
ROC Curve
Cuff
Cardiology
Female
photoplethysmography
business
Zdroj: Sensors
Volume 21
Issue 7
Sensors (Basel, Switzerland)
Sensors, Vol 21, Iss 2446, p 2446 (2021)
ISSN: 1424-8220
DOI: 10.3390/s21072446
Popis: Deep vein thrombosis (DVT) of lower limbs can easily arise from prolonged sitting or standing. Elders and pregnant women are most likely to have this disease. When the embolus of DVT comes to pass the lung, it will become a life-threatening disease. Thus, for DVT disease, early detection and the early treatment are needed. The goal of this study was to develop an examination system to be used at non-medical places to detect the DVT of lower limbs with light reflection rheography (LRR). Consisting of a wearable device and a mobile application (APP), the system is operated in a wireless manner to control the actions of sensors and display and store the LRR signals on the APP. Then, the recorded LRR signals are processed to find the parameters of DVT examination. Twenty subjects were recruited to perform experiments. The veins of lower limbs were occluded by pressuring the cuff up to 100 mmHg and 150 mmHg to simulate the slight and serious DVT scenarios, respectively. Six characteristic parameters were defined to classify whether there was positive or negative DVT using the receiver operating characteristic curves, including the slopes of emptying and refilling curves in the LRR signal, and the changes of venous pump volume. Under the slight DVT scenario (0 mmHg vs. 100 mmHg), the first three parameters, m10, m40, and m50, had accuracies of 72%, 69%, and 69%, respectively. Under the serious DVT scenario (0 mmHg vs. 150 mmHg), m10, m40, and m50 achieved accuracies of 73%, 76%, and 73%, respectively. The experimental results show that this proposed examination system may be practical as an auxiliary tool to screen DVT in homecare settings.
Databáze: OpenAIRE