A rare case of primary malignant melanoma of the scrotum diagnosed by fine-needle aspiration
Autor: | Konstantina Damala, Dimitrios Peschos, Elena Tsanou, Vassiliki Malamou-Mitsi, Niki J. Agnantis, Evdoxia Sintou-Mantela, Lina Pappa |
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Rok vydání: | 2004 |
Předmět: |
Male
Pathology medicine.medical_specialty Histology Biopsy Fine-Needle Physical examination Pathology and Forensic Medicine Lesion Antigen Cytology Scrotum medicine Humans Melanoma medicine.diagnostic_test business.industry General Medicine Genital Neoplasms Male/*pathology Middle Aged medicine.disease Fine-needle aspiration medicine.anatomical_structure Melanoma/*pathology Scrotum/*pathology Genital Neoplasms Male Differential diagnosis medicine.symptom business |
Zdroj: | Diagnostic cytopathology. 31(6) |
ISSN: | 8755-1039 |
Popis: | We report a case of a 55-yr-old man with malignant melanoma of scrotum. He was referred to our Hospital with a complaint of gradual focal enlargement of the scrotum in a period of 3 yr. On physical examination, a pigmented, poorly marginated mass, with central necrosis was observed. A fine-needle aspiration (FNA) of the lesion was performed. Cytological examination revealed highly cellular smears, containing malignant cells, dispersed or arranged in loose aggregates. Cellular morphology and characteristics were identical to those of malignant melanoma arising elsewhere in the skin. The immunocytochemical study revealed positivity of neoplastic cells for anti-melanoma monoclonal antibody (HMB-45) antigen. Histological confirmation finally was provided after wide excision of the lesion. We emphasize the difficulties in differential diagnosis considerations and diagnostic pitfalls of scrotal lesions. Diagn. Cytopathol. 2004;31:413–416. © 2004 Wiley-Liss, Inc. |
Databáze: | OpenAIRE |
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