Prenatal particulate air pollution and DNA methylation in newborns: an epigenome-wide meta-analysis
| Autor: | Tim S. Nawrot, Cheng Peng, Kelly M. Bakulski, Paul Yousefi, Mariona Bustamante, Lorenzo Richiardi, Josep M. Antó, Erik Melén, Göran Pershagen, Dawn L. DeMeo, Jason I. Feinberg, Cheng-Jian Xu, Gerard H. Koppelman, Carrie V. Breton, Inger Kull, Rosalind J. Wright, Akram Ghantous, Diane R. Gold, Charles Auffray, Michelle Plusquin, Nathanaël Lemonnier, Herman T. den Dekker, Johanna Lepeule, Itai Kloog, Christine Ladd-Acosta, Martine Vrijheid, Olena Gruzieva, Isabella Annesi-Maesano, Bert Brunekreef, Heather E. Volk, Janine F. Felix, José Luis Ruiz, Zdenko Herceg, Stephanie J. London, Allan C. Just, Cilla Söderhäll, Simon Kebede Merid, Lu Gao, Anna Bergström, Regina Grazuleviciene, Jean Bousquet, Vincent W. V. Jaddoe, Andrea A. Baccarelli, Liesbeth Duijts, Jordi Sunyer, Costanza Pizzi, Juha Kere, Caroline L Relton, Franca Rusconi, Manolis Kogevinas, Ulrike Gehring, Kristine B. Gutzkow, Paolo Vineis, Carles Hernandez-Ferrer |
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| Přispěvatelé: | STEMM - Stem Cells and Metabolism Research Program, Juha Kere / Principal Investigator, University Management, Research Programs Unit, Karolinska Institutet [Stockholm], Stockholm County Council, University of Groningen [Groningen], University of Bristol [Bristol], University of Southern California (USC), Johns Hopkins Bloomberg School of Public Health [Baltimore], Johns Hopkins University (JHU), University of Michigan [Ann Arbor], University of Michigan System, European Institute for Systems Biology and Medicine (EISBM), Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes (UGA), Hasselt University (UHasselt), Imperial College London, International Agency for Cancer Research (IACR), Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), University of Turin, Children’s Hospital A. Meyer [Florence, Italy], Instituto de Salud Global - Institute For Global Health [Barcelona] (ISGlobal), CIBER de Epidemiología y Salud Pública (CIBERESP), Erasmus University Medical Center [Rotterdam] (Erasmus MC), Center for Genomic Regulation (CRG-UPF), Spanish National Research Council (CSIC), Hospital del Mar Medical Research Institute [Barcelone, Espagne] (IMIM), Norwegian Institute of Public Health [Oslo] (NIPH), Vytautas Magnus University - Vytauto Didziojo Universitetas (VDU), Boston Children's Hospital, Institut Pierre Louis d'Epidémiologie et de Santé Publique (iPLESP), Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU), Contre les MAladies Chroniques pour un VIeillissement Actif en Languedoc-Roussillon (MACVIA-LR), Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Université Montpellier 1 (UM1)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO)-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Vieillissement et Maladies chroniques : approches épidémiologique et de santé publique (VIMA), Université de Versailles Saint-Quentin-en-Yvelines (UVSQ)-Institut National de la Santé et de la Recherche Médicale (INSERM), Sachs’ Children and Youth Hospital [Stockholm, Sweden], King‘s College London, Utrecht University [Utrecht], Icahn School of Medicine at Mount Sinai [New York] (MSSM), Harvard Medical School [Boston] (HMS), Harvard T.H. Chan School of Public Health, Ben-Gurion University of the Negev (BGU), National Institute of Environmental Health Sciences [Durham] (NIEHS-NIH), National Institutes of Health [Bethesda] (NIH), Columbia University [New York], European Project: 733206,H2020,H2020-SC1-2016-RTD,LIFECYCLE(2017), European Project, Groningen Research Institute for Asthma and COPD (GRIAC), Epidemiology, Erasmus MC other, Pediatrics, BARBAGALLO, Maïlys, Early-life stressors and LifeCycle health - LIFECYCLE - - H20202017-01-01 - 2021-12-31 - 733206 - VALID, (7e PC / 2007-206) au titre de la convention de subvention n ° 308333 - le projet HELIX - INCOMING, Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Università degli studi di Torino = University of Turin (UNITO), Université Montpellier 1 (UM1)-Centre Hospitalier Régional Universitaire [Montpellier] (CHRU Montpellier)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre Hospitalier Universitaire de Nîmes (CHU Nîmes)-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-European Innovation Partnership on Active and Healthy Ageing Reference Site (EIP on AHA), Commission Européenne-Commission Européenne-Organisation Mondiale de la Santé / World Health Organization Office (OMS / WHO) |
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
[SDE] Environmental Sciences
Male MESH: Air Pollutants Health Toxicology and Mutagenesis [SDV]Life Sciences [q-bio] MESH: Epigenome 010501 environmental sciences SUSCEPTIBILITY Toxicology LUNG DEVELOPMENT 01 natural sciences Cohort Studies Epigenome 0302 clinical medicine MESH: Pregnancy MESH: DNA Methylation MESH: Child Infants nadons 030212 general & internal medicine CORD BLOOD MESH: Maternal Exposure Child Public Environmental & Occupational Health GENE-EXPRESSION Air Pollutants Aire -- Contaminació MESH: Infant Newborn ASSOCIATION ADN -- Metilació Fetal Blood MESH: Infant 3142 Public health care science environmental and occupational health 3. Good health Europe [SDV] Life Sciences [q-bio] Exposome PREGNANCY MESH: Particulate Matter Maternal Exposure Meta-analysis Child Preschool DNA methylation [SDE]Environmental Sciences Female Life Sciences & Biomedicine MESH: Air Pollution Adolescent Adverse outcomes Environmental Sciences & Ecology Environment complex mixtures 03 medical and health sciences Environmental health Air Pollution medicine Humans MESH: Fetal Blood Epigenetics EXPOSURE Prenatal exposure 0105 earth and related environmental sciences MESH: Adolescent Pregnancy MESH: Humans Science & Technology business.industry Research MESH: Child Preschool R-PACKAGE Public Health Environmental and Occupational Health Infant Newborn Infant CHILDHOOD ASTHMA Environmental Sciences DNA Methylation medicine.disease Particulate air pollution MESH: Male Genòmica [SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologie Gene-Environment Interaction Particulate Matter [SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie business MESH: Female MATTER |
| Zdroj: | Gruzieva, O, Xu, C-J, Yousefi, P, Relton, C, Merid, S K, Breton, C V, Gao, L, Volk, H E, Feinberg, J I, Ladd-Acosta, C, Bakulski, K, Auffray, C, Lemonnier, N, Plusquin, M, Ghantous, A, Herceg, Z, Nawrot, T S, Pizzi, C, Richiardi, L, Rusconi, F, Vineis, P, Kogevinas, M, Felix, J F, Duijts, L, den Dekker, H T, Jaddoe, V W V, Ruiz, J L, Bustamante, M, Antó, J M, Sunyer, J, Vrijheid, M, Gutzkow, K B, Grazuleviciene, R, Hernandez-Ferrer, C, Annesi-Maesano, I, Lepeule, J, Bousquet, J, Bergström, A, Kull, I, Söderhäll, C, Kere, J, BIOS Consortium, Gehring, U, Brunekreef, B, Just, A C, Wright, R J, Peng, C, Gold, D R, Kloog, I, DeMeo, D L & Pershagen, G 2019, ' Prenatal Particulate Air Pollution and DNA Methylation in Newborns : An Epigenome-Wide Meta-Analysis ', Environmental Health Perspectives, vol. 127, no. 5, 057012 . https://doi.org/10.1289/EHP4522 Environmental Health Perspectives Environmental Health Perspectives, National Institute of Environmental Health Sciences, 2019, 127 (5), pp.057012. ⟨10.1289/EHP4522⟩ Environmental Health Perspectives, 127(5):057012. US DEPT HEALTH HUMAN SCIENCES PUBLIC HEALTH SCIENCE Environmental Health Perspectives, 127(5):057012. Public Health Services, US Dept of Health and Human Services Environmental Health Perspectives, 2019, 127 (5), pp.057012. ⟨10.1289/EHP4522⟩ Recercat. Dipósit de la Recerca de Catalunya instname Digital.CSIC. Repositorio Institucional del CSIC |
| ISSN: | 0091-6765 1552-9924 |
| DOI: | 10.1289/EHP4522 |
| Popis: | Background: Prenatal exposure to air pollution has been associated with childhood respiratory disease and other adverse outcomes. Epigenetics is a suggested link between exposures and health outcomes. Objectives: We aimed to investigate associations between prenatal exposure to particulate matter (PM) with diameter |
| Databáze: | OpenAIRE |
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