Relationship between retinal ischemia and cardiovascular autonomic damage in diabetes
| Autor: | Luciano Bernardi, Angela Giardullo, Giuliano Marti, L. Ricordi, Pietro Fratino, Giulio Vandelli, Marco Rossi |
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| Rok vydání: | 1989 |
| Předmět: |
Male
medicine.medical_specialty Valsalva Maneuver Endocrinology Diabetes and Metabolism medicine.medical_treatment Posture Diaphragmatic breathing Blood Pressure Autonomic Nervous System Endocrinology Diabetic Neuropathies Heart Rate Ischemia Internal medicine Diabetes mellitus Internal Medicine medicine Valsalva maneuver Humans Vagal tone Fluorescein Angiography Diabetic Retinopathy medicine.diagnostic_test business.industry Respiration Retinal Vessels General Medicine Diabetic retinopathy Middle Aged medicine.disease Fluorescein angiography Blood pressure Diabetes Mellitus Type 1 Diabetes Mellitus Type 2 Anesthesia Cardiology Female business Retinopathy |
| Zdroj: | Acta diabetologica latina. 26(3) |
| ISSN: | 0001-5563 |
| Popis: | In order to investigate the relationship between ischemic diabetic retinopathy and cardiac autonomic dysfunction we studied 40 diabetic patients (mean age +/- SEM: 48 +/- 2 years). Retinopathy was evaluated by fluorescein angiography and patients were divided into three groups: a) with ischemic retinopathy (15 patients), b) with edematous retinopathy (13 patients) and c) without retinopathy (12 patients). Cardiac autonomic function was assessed by 4 tests based on cardiovascular reflexes (heart rate response to Valsalva maneuver and to deep breathing; systolic blood pressure fall after standing and diastolic blood pressure rise during handgrip) and by the cross-correlation test, a computerized technique for the analysis of respiratory sinus arrhythmia based on spectral analysis of electrocardiographic and respiratory signals. Abnormalities of cardiac autonomic tests were present in 26/40 patients (65%); considering the retinal angiographic classification, autonomic test abnormalities were found in 13/15 (86.6%) patients with ischemic retinopathy, in 7/13 (53.9%) patients with edematous retinopathy and in 6/12 (50%) patients without retinopathy. The prevalence of cardiac autonomic dysfunction was significantly higher (p less than 0.005) in the ischemic retinopathy group compared to the other groups. These results show a strong association between ischemic retinopathy and cardiac autonomic dysfunction. |
| Databáze: | OpenAIRE |
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