Anticarcinoembryonic antigen immunoscintigraphy with a 99mTc-Fab′ fragment (Immu 4TM) in primary and recurrent colorectal cancer
| Autor: | H. Cesnik, P. Lind, P. Lechner, G. Binter |
|---|---|
| Rok vydání: | 1993 |
| Předmět: |
Adult
medicine.medical_specialty Colorectal cancer Rectum Immunoscintigraphy Immunoglobulin Fab Fragments Carcinoembryonic antigen Surgical oncology medicine Humans Neoplasm Metastasis Prospective cohort study Radiation treatment planning Aged Aged 80 and over Tomography Emission-Computed Single-Photon biology business.industry Gastroenterology Antibodies Monoclonal Technetium General Medicine Middle Aged medicine.disease Colorectal surgery Carcinoembryonic Antigen Surgery medicine.anatomical_structure Radioimmunodetection biology.protein Radiology Neoplasm Recurrence Local Colorectal Neoplasms business |
| Zdroj: | Diseases of the Colon & Rectum. 36:930-935 |
| ISSN: | 0012-3706 |
| DOI: | 10.1007/bf02050628 |
| Popis: | Forty-seven patients were submitted to 68 radioimmunoscintigraphic investigations for primary or recurrent colorectal cancer. Immunoscintigraphy with Immu-4 tm correctly detected 28 primary colorectal cancers of 29 and 12 of 12 recurrent colorectal cancers. Overall accuracy was 93.75 percent in primary and 91.6 percent in recurrent colorectal cancer. Immunoscintigraphy had a decisive influence on treatment planning in every third primary colorectal cancer patient and was by far superior to CT scan in the detection of early recurrences, especially in patients with a history of abdominoperineal or low anterior resection. Immu-4 tm scintigraphy is a safe and convenient diagnostic approach to colorectal cancer. Because radioactivity is acceptably low and the method is absolutely free of side effects, there are no objections to the repeated use of immunoscintigraphy which provides important information in primary diagnosis as well as in the follow-up of colorectal cancer patients. |
| Databáze: | OpenAIRE |
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