Efficacy and potential mechanisms of Chinese herbal compounds in coronavirus disease 2019: advances of laboratory and clinical studies
| Autor: | Li-Hua Sun, Liu-Cheng Li, Jing-Jing Yao, Cheng-Tao Jin, Mu-Feng Xiang, Zhi-Hui Zhang |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
Chinese herbal compounds Coronavirus disease 2019 (COVID-19) Review medicine.disease_cause law.invention Other systems of medicine Randomized controlled trial law Pandemic Medicine Medical prescription Intensive care medicine Coronavirus Pharmacology business.industry SARS-CoV-2 Public health COVID-19 medicine.disease Complementary and alternative medicine Medicinal herbs business Cytokine storm RZ201-999 |
| Zdroj: | Chinese Medicine, Vol 16, Iss 1, Pp 1-13 (2021) Chinese Medicine |
| ISSN: | 1749-8546 |
| Popis: | The Coronavirus disease 2019 (COVID-19) pandemic is still spread and has made a severe public health threat around the world. To improve disease progression, emerging Chinese herbal compounds were used in clinical practice and some agents have proven beneficial in treating COVID-19. Here, the relevant literature from basic researches to clinical application were identified and comprehensively assessed. A variety of Chinese herbal compounds have been reported to be effective in improving symptoms and outcomes in patients with COVID-19, particularly together with routine treatment strategy. The pharmacological activities were mainly attributed to the relief of clinical symptoms, inhibition of cytokine storm, and improvement of organ function. Besides, the development of novel antiviral drugs from medicinal herbs were further discussed. The updated laboratory and clinical studies provided the evidence of Chinese herbal compounds such as Lianhua Qingwen prescription, Shufeng Jiedu prescription, and Qingfei Paidu Tang for the relief of COVID-19. However, both of the randomized controlled trials and real world researches need to be done for supporting the evidence including the efficacy and safety in fighting COVID-19. |
| Databáze: | OpenAIRE |
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