Non-Traumatic Intramuscular Hip Hematoma in a Cirrhotic Patient With Hepatocellular Carcinoma and Portal Vein Thrombosis Treated With Sorafenib and Low Molecular Weight Heparin
| Autor: | Christos Sotiropoulos, Konstantinos C Thomopoulos |
|---|---|
| Rok vydání: | 2021 |
| Předmět: |
Sorafenib
medicine.medical_specialty Cirrhosis medicine.drug_class Intramuscular hematoma Low molecular weight heparin 030204 cardiovascular system & hematology hip hematoma Gastroenterology 03 medical and health sciences 0302 clinical medicine Hematoma Internal medicine Internal Medicine medicine portal vein thrombosis business.industry cirrhosis low molecular weight heparin General Engineering hepatocellular carcinoma medicine.disease digestive system diseases Portal vein thrombosis Oncology Hepatocellular carcinoma sorafenib Complication business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Cureus |
| ISSN: | 2168-8184 |
| Popis: | Hepatocellular carcinoma (HCC) is a common neoplasm amongst cirrhotic patients and portal vein thrombosis (PVT) is an often found complication. Sorafenib and low molecular weight heparin (LMWH) are considered part of the gold-standard treatment of such patients. Spontaneous intramuscular hematomas of the limbs induced by these agents, as an adverse event, are generally rare. We present a 66-year-old male patient with liver cirrhosis, HCC and PVT treated with Sorafenib and LMWH who developed a non-traumatic hip hematoma. Simple elevation of the lower limb and blood-products infusion was successful in leading to resolution of the symptoms. As the popularity of these agents increases, healthcare providers need to be aware of such treatment adverse events. |
| Databáze: | OpenAIRE |
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