Urinary tissue factor activity in colorectal disease

Autor: I. Taylor, K. Ei‐Baruni, O. S. Roath, J.L. Francis, N. J. Carty
Rok vydání: 1990
Předmět:
Zdroj: British Journal of Surgery. 77:1091-1094
ISSN: 1365-2168
0007-1323
Popis: Procoagulant activity (PCA) in normal urine has been recognized for over 50 years. Although tissue factor (TF) is produced by certain tumours, and is increased in both tumour-associated macrophages and blood monocytes, the possibility that it might also be increased in urine has not been studied in patients with cancer. We have measured urinary PCA in hospital controls without inflammatory or neoplastic disease (n = 79), in patients with rheumatoid arthritis (n = 8), inflammatory bowel disease (n = 79), colorectal cancer (n = 70) and in patients undergoing colonoscopy (n = 50). Urinary PCA was higher (P
Databáze: OpenAIRE