Comparison of the effects of intraocular irrigating solutions on the corneal endothelium in intraocular lens implantation
Autor: | Yuichi Ohashi, Mamoru Matsuda, T Omoto, H. Yoshida, H Okamoto, H Hosotani, Shigeru Kinoshita, Yoshikazu Shimomura, Nobuyuki Ohguro |
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Rok vydání: | 1991 |
Předmět: |
medicine.medical_specialty
Corneal endothelium Endothelium genetic structures medicine.medical_treatment Eye disease Bicarbonate Intraocular lens Cell Count Cellular and Molecular Neuroscience chemistry.chemical_compound Corneal edema Ophthalmology medicine Humans Prospective Studies Prospective cohort study Aged Aged 80 and over Lenses Intraocular business.industry Corneal Edema Endothelium Corneal Middle Aged medicine.disease Glutathione Sensory Systems eye diseases Bicarbonates Drug Combinations medicine.anatomical_structure chemistry IRRIGATING SOLUTIONS sense organs Ophthalmic Solutions business Research Article |
Zdroj: | The British journal of ophthalmology. 75(8) |
ISSN: | 0007-1161 |
Popis: | We conducted a randomised prospective controlled study to determine the effects of a glucose glutathione bicarbonate solution (BSS Plus) and a citrate acetate bicarbonate solution (S-MA2) on the corneal endothelium in patients undergoing extracapsular cataract extraction with posterior chamber lens implantation. One eye of each patient was randomly assigned to receive BSS Plus, and the other eye to receive S-MA2. BSS Plus caused significantly less corneal swelling on the first postoperative day than did S-MA2. There was no difference between the two solutions in their effect on corneal thickness one week and one month postoperatively. Computer assisted morphometric analysis of wide-field specular microscopic photographs demonstrated minimal changes in endothelial morphological characteristics in the eyes irrigated with BSS Plus. By comparison S-MA2, caused a significant loss of endothelial cells and a marked reduction in the figure coefficient. These results indicated that BSS Plus has a clinical advantage over S-MA2 with respect to the corneal endothelium. |
Databáze: | OpenAIRE |
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